Marcus Burnett is a hen-pecked family man. Mike Lowry is a foot-loose and fancy free ladies' man. Both are Miami policemen, and both have 72 hours to reclaim a consignment of drugs stolen from under their station's nose. To complicate matters, in order to get the assistance of the sole witness to a murder, they have to pretend to be each other.
Out-of-control, trash-talking buddy cops Marcus Burnett and Mike Lowrey of the Miami Narcotics Task Force reunite, and bullets fly, cars crash and laughs explode as they pursue a whacked-out drug lord from the streets of Miami to the barrios of Cuba. But the real fireworks result when Marcus discovers that playboy Mike is secretly romancing Marcus’ sexy sister.
Back in sunny southern California and on the trail of two murderers, Axel Foley again teams up with LA cop Billy Rosewood. Soon, they discover that an amusement park is being used as a front for a massive counterfeiting ring – and it's run by the same gang that shot Billy's boss.
When a CIA operation to purchase classified Russian documents is blown by a rival agent, who then shows up in the sleepy seaside village where Bourne and Marie have been living. The pair run for their lives and Bourne, who promised retaliation should anyone from his former life attempt contact, is forced to once again take up his life as a trained assassin to survive.
Simon Phoenix, a violent criminal cryogenically frozen in 1996, escapes during a parole hearing in 2032 in the utopia of San Angeles. Police are incapable of dealing with his violent ways and turn to his captor, who had also been cryogenically frozen after being wrongfully accused of killing 30 innocent people while apprehending Phoenix.
When the government puts all its rotten criminal eggs in one airborne basket, it's asking for trouble. Before you can say, "Pass the barf bag," the crooks control the plane, led by creepy Cyrus "The Virus" Grissom. Watching his every move is the just-released Cameron Poe, who'd rather reunite with his family.
Axel heads for the land of sunshine and palm trees to find out who shot police Captain Andrew Bogomil. Thanks to a couple of old friends, Axel's investigation uncovers a series of robberies masterminded by a heartless weapons kingpin—and the chase is on.
El Mariachi, a musician, arrives in a Mexican town and is mistaken as a hit-man. He runs into trouble with a local drug lord and seeks to avenge the death of his lover.