Joselito "Tito" Escalera (Tito Sotto) - One half of the Escalera brothers, who plots harebrained schemes in every episode. Josemari "Joey" Escalera (Joey De Leon) - The other Escalera sibling. Miss Tapia has a crush on him. Victorio "Vic" Ungasis (Vic Sotto) - the good-looking and smart teacher's pet with a chick-magnet personality. The Escaleras often pick on him during class. Later became a professor of Wanbol University. Liwayway Gawgaw Tapia aka Miss Tapia (Mely Tagasa) - Wanbol University's resident professor who often gets on the Escalera brothers' nerves. Although she admires Joey, Miss Tapia was romantically connected with Mang Temi.Her favorite student is Victorio Ungasis
Vic Ungasis is an archaeologist who has recovered the Kali of Humabon and is looking for a partner sword, the Kampilan of Lapu-Lapu, plus the Peseta, one of Judas Iscariot's 30 pieces of silver which reportedly gives the bearer immortality. Upon returning home, he reunites with the Escalera brothers, who have become successful real-estate developers. However, a Yakuza who has acquired the Kampilan wants the Peseta so it could be merged with the sword for unmatched power.
Iskul Bukol was a Philippine situational comedy show that aired on the IBC 13 network from 1977 to 1990. It starred Filipino comedians Tito Sotto, Vic Sotto, and Joey de Leon. The show centered on their lives as students of the fictional Wanbol University, parodying its real life counterpart, Arellano University. The show's theme song, also titled "Iskul Bukol", is sung to the tune of Elvis Presley's "All Shook Up."